Mathematical Modelling of Blood Flow: Analysing the Impact of Arterial Stenosis and Nanoparticle Suspensions
DOI:
https://doi.org/10.31305/rrijm.2025.v10.n11.031Keywords:
Blood flow dynamics, Arterial stenosis, Mathematical modeling, Non-Newtonian fluid, Hemodynamics, Nanoparticle suspensions, Drug delivery, Cardiovascular diseasesAbstract
Blood flow dynamics play a fundamental role in understanding cardiovascular health and disease, influencing oxygen transport, nutrient delivery, and therapeutic agent distribution. Arterial stenosis, characterized by the narrowing of blood vessels, disrupts normal hemodynamics and contributes to conditions such as hypertension and atherosclerosis. This study employs mathematical modeling to analyze blood flow in stenosed arteries, emphasizing the impact of nanoparticle suspensions on hemodynamics. Using non-Newtonian fluid dynamics, the research examines viscosity variations, velocity profiles, and pressure distribution in stenosed regions, validated through numerical simulations. Additionally, the study explores the role of nanoparticles in modifying blood properties and enhancing drug delivery by evaluating their dispersion and interaction with blood components. The findings provide insights into optimizing therapeutic strategies for cardiovascular diseases, demonstrating the potential of mathematical modeling and nanoparticle technology in advancing targeted treatments and improving circulatory efficiency.
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